2. Path to Resistance

  1. Patricia L. Keen2 and
  2. Mark H. M. M. Montforts3
  1. Vivian Miao,
  2. Dorothy Davies and
  3. Julian Davies

Published Online: 7 DEC 2011

DOI: 10.1002/9781118156247.ch2

Antimicrobial Resistance in the Environment

Antimicrobial Resistance in the Environment

How to Cite

Miao, V., Davies, D. and Davies, J. (2011) Path to Resistance, in Antimicrobial Resistance in the Environment (eds P. L. Keen and M. H. M. M. Montforts), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118156247.ch2

Editor Information

  1. 2

    Faculty of Applied Science, University of British Columbia, Vancouver, British Columbia, Canada

  2. 3

    National Institute for Public Health and the Environment, Bilthoven, The Netherlands

Author Information

  1. Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada

Publication History

  1. Published Online: 7 DEC 2011
  2. Published Print: 30 DEC 2011

ISBN Information

Print ISBN: 9780470905425

Online ISBN: 9781118156247

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Keywords:

  • path to resistance, AR mechanisms;
  • perception of AR, changing with “R-factors”;
  • proto-AR gene, minimizing exposure of new compounds

Summary

This chapter contains sections titled:

  • Introduction

  • A Little History: “The Writing was on the Wall”

  • Mechanisms of Antibiotic Resistance

  • R-Factors: Purveyors of Extrachromosomal AR Genes

  • Origins of Extrachromosomal Resistance Genes: Metagenomic Studies of AR

  • Adapting AR Genes

  • Concluding Remarks

  • References