4. Ecological and Clinical Consequences of Antibiotic Subsistence by Environmental Microbes

  1. Patricia L. Keen3 and
  2. Mark H. M. M. Montforts4
  1. Gautam Dantas1 and
  2. Morten O. A. Sommer2

Published Online: 7 DEC 2011

DOI: 10.1002/9781118156247.ch4

Antimicrobial Resistance in the Environment

Antimicrobial Resistance in the Environment

How to Cite

Dantas, G. and Sommer, M. O. A. (2011) Ecological and Clinical Consequences of Antibiotic Subsistence by Environmental Microbes, in Antimicrobial Resistance in the Environment (eds P. L. Keen and M. H. M. M. Montforts), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118156247.ch4

Editor Information

  1. 3

    Faculty of Applied Science, University of British Columbia, Vancouver, British Columbia, Canada

  2. 4

    National Institute for Public Health and the Environment, Bilthoven, The Netherlands

Author Information

  1. 1

    Department of Pathology and Immunology, Center for Genome Sciences and Systems Biology, Washington University, St. Louis, Missouri, USA

  2. 2

    Department of Systems Biology, Technical University of Denmark, Kgs. Lyngby, Denmark

Publication History

  1. Published Online: 7 DEC 2011
  2. Published Print: 30 DEC 2011

ISBN Information

Print ISBN: 9780470905425

Online ISBN: 9781118156247

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Keywords:

  • antibiotic subsistence by microbes, ecological, clinical;
  • resistance genes, antibiotic subsistome and ecological;
  • new systemswide molecular methods and subsistome

Summary

This chapter contains sections titled:

  • Introduction

  • Environmental Origins of Resistance: The Producer Hypothesis

  • Resistome of other Soil Bacteria: Response to the Producers?

  • Early Reports of Antibiotic Catabolism by Soil Bacteria

  • The Antibiotic Subsistome: Who and how much?

  • Antibiotic Subsistence as a Scavenger Phenotype

  • Ecological Consequences of the Antibiotic Subsistome

  • Investigating Connections Between Subsistomes and Resistomes

  • Metagenomic Functional Selections for Discovering Genes Enabling Antibiotic Subsistence and Resistance

  • Antibiotic Subsistence by Pathogenic Bacteria

  • Concluding Remarks

  • References