45. Polymers

  1. Mike S. Lee
  1. Maurizio S. Montaudo and
  2. Salvatore Battiato

Published Online: 21 MAY 2012

DOI: 10.1002/9781118180730.ch45

Mass Spectrometry Handbook

Mass Spectrometry Handbook

How to Cite

Montaudo, M. S. and Battiato, S. (2012) Polymers, in Mass Spectrometry Handbook (ed M. S. Lee), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118180730.ch45

Editor Information

  1. Milestone Development Services, USA

Author Information

  1. Institute of Chemistry and Technology of Polymers, National Research Council of Italy, Catania, Italy

Publication History

  1. Published Online: 21 MAY 2012
  2. Published Print: 18 APR 2012

Book Series:

  1. Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods

Book Series Editors:

  1. Mike S. Lee

Series Editor Information

  1. Milestone Development Services, USA

ISBN Information

Print ISBN: 9780470536735

Online ISBN: 9781118180730



  • polymers;
  • polymers and MMD, end groups capping repeat units;
  • calibration of the SEC trace using PS standards, a common practice;
  • nanoESI, droplets in close proximity to MS inlet, ionization efficiency enhancement;
  • MALDI in combination with most chromatographic techniques


This chapter contains sections titled:

  • Introduction

  • ESI

  • ESI and Polymers with A Broad MMD

  • Nanoelectrospay Ionization

  • Atmospheric Pressure Electrospray Ionization

  • Desorption Electrospray Ionization

  • Ion Mobility Separation


  • MALDI Matrices

  • MALDI Sample Preparation

  • Differentiating Linear and Cyclic Chains by MALDI

  • Comparing MALDI Spectra and Size Exclusion Chromatograms

  • MALDI and Polymers with A Broad MMD

  • The Offline Combination of MALDI and SEC

  • Optimization of the SEC–MALDI Method

  • MALDI and other Chromatographic Techniques

  • MALDI of Copolymers and other Complex Polymers

  • Tandem Mass Spectrometry

  • References