49. High-Performance Thin-Layer Chromatography–Mass Spectrometry for Analysis of Small Molecules

  1. Mike S. Lee
  1. Gertrud E. Morlock

Published Online: 21 MAY 2012

DOI: 10.1002/9781118180730.ch49

Mass Spectrometry Handbook

Mass Spectrometry Handbook

How to Cite

Morlock, G. E. (2012) High-Performance Thin-Layer Chromatography–Mass Spectrometry for Analysis of Small Molecules, in Mass Spectrometry Handbook (ed M. S. Lee), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118180730.ch49

Editor Information

  1. Milestone Development Services, USA

Author Information

  1. Institute of Food Chemistry, University of Hohenheim, Stuttgart, Germany

Publication History

  1. Published Online: 21 MAY 2012
  2. Published Print: 18 APR 2012

Book Series:

  1. Wiley Series on Pharmaceutical Science and Biotechnology: Practices, Applications and Methods

Book Series Editors:

  1. Mike S. Lee

Series Editor Information

  1. Milestone Development Services, USA

ISBN Information

Print ISBN: 9780470536735

Online ISBN: 9781118180730

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Keywords:

  • HPTLC–MS in small molecule analysis;
  • HPTLC, complementary to HPLC;
  • offline flexible system, adaptive to sample, with HPTLC as required;
  • coupling TLC/HPTLC with MS;
  • HPTLC-DART-MS signals of compounds, and coupling with HPTLC

Summary

This chapter contains sections titled:

  • High-Performance Thin-Layer Chromatography

  • Coupling to Mass Spectrometry

  • Commercially Available HPTLC-MS Systems

  • Comparison of the Approaches and Outlook

  • References