10. Targeted Therapy Design

  1. Guosheng Yin

Published Online: 9 JAN 2012

DOI: 10.1002/9781118183335.ch10

Clinical Trial Design: Bayesian and Frequentist Adaptive Methods

Clinical Trial Design: Bayesian and Frequentist Adaptive Methods

How to Cite

Yin, G. (2011) Targeted Therapy Design, in Clinical Trial Design: Bayesian and Frequentist Adaptive Methods, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118183335.ch10

Publication History

  1. Published Online: 9 JAN 2012
  2. Published Print: 19 DEC 2011

ISBN Information

Print ISBN: 9780470581711

Online ISBN: 9781118183335

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Keywords:

  • cytostatic agents;
  • prognostic biomarkers;
  • predictive biomarkers;
  • targeted therapy design;
  • randomized discontinuation design

Summary

This chapter contains sections titled:

  • Cytostatic Agents

  • Prognostic and Predictive Biomarkers

  • Predictive Biomarker Validation

  • Randomized Discontinuation Design

  • Adaptive Signature Design

  • Adaptive Threshold Design