6. Phase III Trial Design

  1. Guosheng Yin

Published Online: 9 JAN 2012

DOI: 10.1002/9781118183335.ch6

Clinical Trial Design: Bayesian and Frequentist Adaptive Methods

Clinical Trial Design: Bayesian and Frequentist Adaptive Methods

How to Cite

Yin, G. (2011) Phase III Trial Design, in Clinical Trial Design: Bayesian and Frequentist Adaptive Methods, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118183335.ch6

Publication History

  1. Published Online: 9 JAN 2012
  2. Published Print: 19 DEC 2011

ISBN Information

Print ISBN: 9780470581711

Online ISBN: 9781118183335

SEARCH

Keywords:

  • statistical hypothesis;
  • exponential distribution;
  • superiority trial;
  • noninferiority trial;
  • equivalence trial

Summary

This chapter contains sections titled:

  • Power and Sample Size

  • Comparing Means for Continuous Outcomes

  • Comparing Proportions for Binary Outcomes

  • Sample Size with Survival Data

  • Sample Size for Correlated Data

  • Group Sequential Methods

  • Adaptive Designs

  • Causality and Noncompliance

  • Post-Approval Trial—Phase IV