8. Late-Onset Toxicity

  1. Guosheng Yin

Published Online: 9 JAN 2012

DOI: 10.1002/9781118183335.ch8

Clinical Trial Design: Bayesian and Frequentist Adaptive Methods

Clinical Trial Design: Bayesian and Frequentist Adaptive Methods

How to Cite

Yin, G. (2011) Late-Onset Toxicity, in Clinical Trial Design: Bayesian and Frequentist Adaptive Methods, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118183335.ch8

Publication History

  1. Published Online: 9 JAN 2012
  2. Published Print: 19 DEC 2011

ISBN Information

Print ISBN: 9780470581711

Online ISBN: 9781118183335

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Keywords:

  • censored data;
  • dose-finding algorithm;
  • fractional continual reassessment method;
  • weighted binomial likelihood;
  • numerical comparison

Summary

This chapter contains sections titled:

  • Missing Data with Delayed Outcomes

  • Fractional 3 + 3 Design

  • Fractional Continual Reassessment Method

  • Time-to-Event Continual Reassessment Method

  • EM Continual Reassessment Method