9. Drug-Combination Trials
Published Online: 9 JAN 2012
DOI: 10.1002/9781118183335.ch9
Copyright © 2012 John Wiley & Sons, Inc. All rights reserved.
Book Title
Clinical Trial Design: Bayesian and Frequentist Adaptive Methods
Additional Information
How to Cite
Yin, G. (2011) Drug-Combination Trials, in Clinical Trial Design: Bayesian and Frequentist Adaptive Methods, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118183335.ch9
Publication History
- Published Online: 9 JAN 2012
- Published Print: 19 DEC 2011
Book Series:
ISBN Information
Print ISBN: 9780470581711
Online ISBN: 9781118183335
- Summary
- Chapter
Keywords:
- sequential dose-finding scheme;
- copula-type regression;
- clayton-type model;
- bivariate binary outcomes;
- latent contingency table
Summary
This chapter contains sections titled:
Why Are Drugs Combined?
New Challenges
Sequential Dose-Finding Scheme
Dose Finding with Copula-Type Regression
Latent Contingency Table Approach
Phase I/II Drug-Combination Trial
Summary