2. Immunoliposomes for Cardiovascular Targeting

  1. Yashwant Pathak2 and
  2. Simon Benita3
  1. Tatyana Levchenko,
  2. William Hartner and
  3. Vladimir P. Torchilin

Published Online: 23 APR 2012

DOI: 10.1002/9781118229019.ch2

Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications

Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications

How to Cite

Levchenko, T., Hartner, W. and Torchilin, V. P. (2012) Immunoliposomes for Cardiovascular Targeting, in Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications (eds Y. Pathak and S. Benita), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118229019.ch2

Editor Information

  1. 2

    Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida, USA

  2. 3

    The Institute for Drug Research of the School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

Author Information

  1. The Center for Pharmaceutical Biotechnology and Nanomedicine, Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts, USA

Publication History

  1. Published Online: 23 APR 2012
  2. Published Print: 11 MAY 2012

ISBN Information

Print ISBN: 9780470612811

Online ISBN: 9781118229019



  • immunoliposomes and cardiovascular targeting;
  • endothelial cell liposome internalization via avidin–biotin;
  • atherosclerotic lesions in imaging;
  • thrombolytic therapy with immunoliposomes;
  • ischemia, gene therapy, immunoliposomes and affected heart


This chapter contains sections titled:

  • Introduction

  • Immunoliposome Targeting to Pathological Regions of the Vessel Wall

  • Liposome Internalization by Endothelial Cells

  • Targeting of Atherosclerotic Lesions for Tomographic Imaging

  • Antibody-Mediated Liposomes for Diagnosis of Thrombosis

  • Thrombolytic Therapy with Immunoliposomes

  • Targeted Sealing of Cell Membrane Lesions: Preservation of Cell Viability

  • Accumulation of Liposomes and Immunoliposomes in the Ischemic Heart

  • Immunoliposomes as a Drug and Gene Delivery Vehicle to the Infarcted Heart

  • References