20. Antibody-Mediated Arthritis and New Therapeutic Avenues

  1. Yashwant Pathak2 and
  2. Simon Benita3
  1. Kutty Selva Nandakumar

Published Online: 23 APR 2012

DOI: 10.1002/9781118229019.ch20

Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications

Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications

How to Cite

Nandakumar, K. S. (2012) Antibody-Mediated Arthritis and New Therapeutic Avenues, in Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications (eds Y. Pathak and S. Benita), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118229019.ch20

Editor Information

  1. 2

    Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida, USA

  2. 3

    The Institute for Drug Research of the School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

Author Information

  1. Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden

Publication History

  1. Published Online: 23 APR 2012
  2. Published Print: 11 MAY 2012

ISBN Information

Print ISBN: 9780470612811

Online ISBN: 9781118229019

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Keywords:

  • antibody-mediated arthritis and new therapeutic avenues;
  • autoantibodies in rheumatoid arthritis;
  • cartilage antigen-specific antibodies, inducing arthritis;
  • cartilage damage, independent of inflammatory mediators;
  • arthritis attenuation, of specific sugars on IgG

Summary

This chapter contains sections titled:

  • Autoantibodies in Rheumatoid Arthritis

  • Role of Cartilage Antigen-Specific Antibodies in Inducing Arthritis

  • Arthritis Mediation Through Antibodies Recognizing Citrullinated Antigens

  • Regulation at the Effector Level

  • Cartilage Damage Independent of Inflammatory Mediators

  • pathogenicity of GPI-Specific Antibodies

  • Therapeutic Cleavage of Arthritogenic Antibodies

  • Arthritis Attenuation Though Removal of Specific Sugars on IgG

  • References