5. Mathematical Models of Anti-TNF Therapies and their Correlation with Tuberculosis

  1. Yashwant Pathak3 and
  2. Simon Benita4
  1. Simeone Marino1,
  2. Mohammad Fallahi-Sichani2,
  3. Jennifer J. Linderman2 and
  4. Denise E. Kirschner1

Published Online: 23 APR 2012

DOI: 10.1002/9781118229019.ch5

Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications

Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications

How to Cite

Marino, S., Fallahi-Sichani, M., Linderman, J. J. and Kirschner, D. E. (2012) Mathematical Models of Anti-TNF Therapies and their Correlation with Tuberculosis, in Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications (eds Y. Pathak and S. Benita), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118229019.ch5

Editor Information

  1. 3

    Department of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida, USA

  2. 4

    The Institute for Drug Research of the School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel

Author Information

  1. 1

    Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA

  2. 2

    Department of Chemical Engineering, College of Engineering, University of Michigan, Ann Arbor, Michigan, USA

Publication History

  1. Published Online: 23 APR 2012
  2. Published Print: 11 MAY 2012

ISBN Information

Print ISBN: 9780470612811

Online ISBN: 9781118229019

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Keywords:

  • mathematical models of anti-TNF, and TB;
  • TNF and anti-TNF drugs, functional, biochemical characteristics;
  • TB infection, ODE, PDE models, in cellular, tissue dynamics;
  • TB immunology, role and biology of TNF;
  • targeting TNF-level, driving TNF in TB granuloma, as new strategies

Summary

This chapter contains sections titled:

  • Introduction

  • Tuberculosis, TNF, and Anti-TNF Drugs

  • Theoretical Models To Study TB Infection

  • Present and Future Work

  • References