6. Folate

  1. Andrew Salter2,
  2. Dr Helen Wiseman3 and
  3. Gregory Tucker2
  1. Dr Stéphane Ravanel and
  2. Dr Fabrice Rébeillé

Published Online: 21 FEB 2012

DOI: 10.1002/9781118253649.ch6



How to Cite

Ravanel, S. and Rébeillé, F. (2012) Folate, in Phytonutrients (eds A. Salter, H. Wiseman and G. Tucker), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118253649.ch6

Editor Information

  1. 2

    Nutritional Sciences Division, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire, LE12 5RD, UK

  2. 3

    Nutritional Sciences, Diabetes and Nutritional Sciences Division, King's College London, Franklin-Wilkins Building, 150 Stamford Street, London, SE1 9NH, UK

Author Information

  1. Laboratoire de Physiologie Cellulaire Végétale, UMR5168 CNRS- UMR1200 INRA – CEA-Université Joseph Fourier Grenoble I, Institut de Recherches en Technologies et Sciences pour le Vivant – CEA-Grenoble, 17 rue des Martyrs, 38054 Grenoble Cedex 9, France

Publication History

  1. Published Online: 21 FEB 2012
  2. Published Print: 23 MAR 2012

ISBN Information

Print ISBN: 9781405131513

Online ISBN: 9781118253649



  • folate, water-soluble vitamin (B9);
  • cellular folates;
  • C1 metabolism, key reactions;
  • serine–glycine metabolism;
  • histidine catabolism, folate metabolism;
  • MTHFR, role in C1;
  • tetrahydrofolate biosynthesis, in plants;
  • plant THF biosynthetic pathway;
  • catabolism, salvage pathway;
  • folate deficiency diagnosis


This chapter contains sections titled:

  • Introduction

  • One-carbon metabolism

  • Folate synthesis and distribution in plants

  • Physiology of folate in human health and disease

  • Folate bioavailability, requirements and food fortification