6. Improving the Biocompatibility of Dendrimers in Drug Delivery

  1. Yiyun Cheng
  1. Yiwen Li1,
  2. Libo Zhao2 and
  3. Yiyun Cheng3

Published Online: 14 JUN 2012

DOI: 10.1002/9781118275238.ch6

Dendrimer-Based Drug Delivery Systems: From Theory to Practice

Dendrimer-Based Drug Delivery Systems: From Theory to Practice

How to Cite

Li, Y., Zhao, L. and Cheng, Y. (2012) Improving the Biocompatibility of Dendrimers in Drug Delivery, in Dendrimer-Based Drug Delivery Systems: From Theory to Practice (ed Y. Cheng), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118275238.ch6

Editor Information

  1. School of Life Sciences, East China Normal University, P.R. China

Author Information

  1. 1

    Department of Polymer Science, College of Polymer Science and Polymer Engineering, The University of Akron, Akron, OH, USA

  2. 2

    Department of Chemistry, University of Science and Technology of China, P.R. China

  3. 3

    School of Life Sciences, East China Normal University, P.R. China

Publication History

  1. Published Online: 14 JUN 2012
  2. Published Print: 15 JUN 2012

Book Series:

  1. Wiley Series in Drug Discovery and Development

Book Series Editors:

  1. Binghe Wang

ISBN Information

Print ISBN: 9780470460054

Online ISBN: 9781118275238

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Keywords:

  • improved dendrimer biocompatibility in drug delivery;
  • dendrimers and advantages, as drug vehicles;
  • biocompatibility, host response at four levels;
  • surface charge, molecular size, hemolytic, dendrimer degradability;
  • PEGylation, in design of biocompatible contrasts for MRI

Summary

This chapter contains sections titled:

  • Introduction

  • Safety Issues of Dendrimers

  • Designing of Biocompatible Dendrimers for Therapeutic Purposes

  • Conclusions

  • References