10. Summary and Some Simple Approximations

  1. Alex Avdeef1,2

Published Online: 7 MAY 2012

DOI: 10.1002/9781118286067.ch10

Book Title

Absorption and Drug Development: Solubility, Permeability, and Charge State, Second Edition

Absorption and Drug Development: Solubility, Permeability, and Charge State, Second Edition

Additional Information

How to Cite

Avdeef, A. (2012) Summary and Some Simple Approximations, in Absorption and Drug Development: Solubility, Permeability, and Charge State, Second Edition, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118286067.ch10

Author Information

  1. 1

    Cambridge, Massachusetts, USA

  2. 2

    Boston, Massachusetts, USA

Publication History

  1. Published Online: 7 MAY 2012
  2. Published Print: 11 MAY 2012

ISBN Information

Print ISBN: 9781118057452

Online ISBN: 9781118286067

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Keywords:

  • some simple approximations;
  • extrapolation uncertainty in pKa determination, resolved;
  • octanol–water ion-pair, the “diff 3–4” approximation;
  • intestinal permeability, and epithelial cell surface;
  • BCS scheme, and physicochemical profiling
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