7. The Nail in Systemic Disease

  1. Robert Baran MD1,2,
  2. David A. R. de Berker MD3,
  3. Mark Holzberg MD4 and
  4. Luc Thomas MD, PhD5
  1. Mark Holzberg MD

Published Online: 23 MAY 2012

DOI: 10.1002/9781118286715.ch7

Baran & Dawber's Diseases of the Nails and their Management, Fourth Edition

Baran & Dawber's Diseases of the Nails and their Management, Fourth Edition

How to Cite

Holzberg, M. (2012) The Nail in Systemic Disease, in Baran & Dawber's Diseases of the Nails and their Management, Fourth Edition (eds R. Baran, D. A. R. de Berker, M. Holzberg and L. Thomas), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781118286715.ch7

Editor Information

  1. 1

    University of Franche-Comté, Cannes, France

  2. 2

    Gustave Roussy Cancer Institute, Villejuif Nail Disease Center, Cannes, France

  3. 3

    Bristol Dermatology Centre, Bristol Royal Infirmary, Bristol, UK

  4. 4

    Department of Dermatology, Emory University School of Medicine, Atlanta, GA, USA

  5. 5

    Department of Dermatology, Lyon 1 University, Centre Hospitalier Lyon Sud, Pierre Bénite, France

Author Information

  1. Department of Dermatology, Emory University School of Medicine, Atlanta, GA, USA

Publication History

  1. Published Online: 23 MAY 2012
  2. Published Print: 6 JUL 2012

ISBN Information

Print ISBN: 9780470657355

Online ISBN: 9781118286715

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Keywords:

  • Beau's lines;
  • clubbing;
  • half-and-half nails;
  • koilonychias;
  • Muehrcke's lines;
  • nail fold telangiectasias;
  • onycholysis;
  • splinter hemorrhages;
  • Terry's nail;
  • yellow nail syndrome

Summary

The nail may act as a “window” to the body. Changes in the nail shape or color may indicate a systemic disorder or a disease long before other symptoms appear. Examination of clinical nail changes has historically given the observer clues to the patient's underlying systemic illness. Nail changes may provide hints for diseases of cardiac, circulatory, respiratory, gastrointestinal, hepatic, renal, genitourinary, reproductive, endocrine, nervous, psychological, musculoskeletal, hematological, lymphatic, connective tissue, immunological, nutritional and metabolic systems.