8. Drug-induced Nail Changes
- Robert Baran MD3,4,
- David A. R. de Berker MD5,
- Mark Holzberg MD6,
- Luc Thomas MD, PhD7
Published Online: 23 MAY 2012
DOI: 10.1002/9781118286715.ch8
Copyright © 2012 John Wiley & Sons, Ltd
Book Title
Baran & Dawber's Diseases of the Nails and their Management, Fourth Edition
Additional Information
How to Cite
Baran, R., Fouilloux, B. and Robert, C. (2012) Drug-induced Nail Changes, in Baran & Dawber's Diseases of the Nails and their Management, Fourth Edition (eds R. Baran, D. A. R. de Berker, M. Holzberg and L. Thomas), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781118286715.ch8
Editor Information
- 3
University of Franche-Comté, Cannes, France
- 4
Gustave Roussy Cancer Institute, Villejuif Nail Disease Center, Cannes, France
- 5
Bristol Dermatology Centre, Bristol Royal Infirmary, Bristol, UK
- 6
Department of Dermatology, Emory University School of Medicine, Atlanta, GA, USA
- 7
Department of Dermatology, Lyon 1 University, Centre Hospitalier Lyon Sud, Pierre Bénite, France
Publication History
- Published Online: 23 MAY 2012
- Published Print: 6 JUL 2012
ISBN Information
Print ISBN: 9780470657355
Online ISBN: 9781118286715
- Summary
- Chapter
- References
Keywords:
- antifungals;
- antimalarial agents;
- antiretroviral drugs;
- cardiovascular drugs;
- chemotherapeutic agents;
- cyclines;
- drugs;
- nail changes;
- photoonycholysis;
- retinoids;
- toxics
Summary
Many side-effects of drugs on the nails are now well known. Some are classic while others have been recently described. Since the last edition of this book, antineoplastic drugs have been recognized as affecting the nails. Many nail signs have been described with these treatments, including onycholysis, hematomas, perionyxis and pyogenic granuloma. The severity of the discomfort can sometime necessitate cessation of therapy. Besides these new drugs, side-effects observed during treatment with retinoids, cyclines, antiretroviral drugs, cardiovascular drugs and antimalarial drugs are well known. Some side-effects described with new drugs are more confidential [AQ: not sure what you mean by ‘confidential’] such as those seen with anti-TFN, cyclosporine, selenium, antifungals, reverse transcriptase inhibitor therapy, salsalate and interferon. Toxic drugs such as arsenic, silver, mercury, thallium and polychlorinated biphenyls are also responsible for nail changes.