2. Assessment of the Potential Renal Transplant Recipient

  1. Iain A. M. MacPhee2,3 and
  2. Jiří Froněk4,5
  1. Patrick B. Mark and
  2. Alan G. Jardine

Published Online: 11 MAY 2012

DOI: 10.1002/9781118305294.ch2

Handbook of Renal and Pancreatic Transplantation

Handbook of Renal and Pancreatic Transplantation

How to Cite

Mark, P. B. and Jardine, A. G. (2012) Assessment of the Potential Renal Transplant Recipient, in Handbook of Renal and Pancreatic Transplantation (eds I. A. M. MacPhee and J. Froněk), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118305294.ch2

Editor Information

  1. 2

    Division of Clinical Sciences: Renal Medicine, St. George's Healthcare NHS Trust, University of London, London, UK

  2. 3

    Department of Renal Medicine and Transplantation, St. George's Healthcare NHS Trust, Blackshaw Road, London, UK

  3. 4

    Transplant Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

  4. 5

    2nd Medical Faculty, Charles University, Prague, Czech Republic

Author Information

  1. BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK

Publication History

  1. Published Online: 11 MAY 2012
  2. Published Print: 6 JUN 2012

ISBN Information

Print ISBN: 9780470654910

Online ISBN: 9781118305294

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Keywords:

  • Renal transplant;
  • dialysis;
  • cardiovascular disease;
  • cancer;
  • glomerulonephritis;
  • obesity;
  • cigarette smoking;
  • hepatitis;
  • elderly;
  • psychological assessment

Summary

Renal transplantation is the optimal treatment for appropriately selected patients with end-stage renal disease. Optimisation of the recipient's health before transplantation ensures best use of the transplant kidney to prolong graft survival and minimise risks of long-term immunosuppression. Assessment of the potential recipient should avoid undue delay to transplant listing but nonetheless address remediable barriers to transplantation. The transplant operation should not pose such a high peri-operative risk that transplantation cannot be justified. Potential technical (surgical) obstacles to transplantation should be identified and resolved where possible. The assessment process can address other co-morbid conditions, including cardiovascular, respiratory and gastroenterological disease. Lifestyle issues such as smoking and obesity may be discussed. Likelihood of recurrence of primary renal disease following transplantation can be considered and pre-emptive preventative strategies be planned. Prior malignancy is a relative contraindication to transplantation and the oncological history can inform risk of tumour recurrence with immunosuppression.