1. Transition Metal Catalysis in the Pharmaceutical Industry

  1. Matthew L. Crawley2 and
  2. Barry M. Trost3
  1. Carl A. Busacca,
  2. Daniel R. Fandrick,
  3. Jinhua J. Song and
  4. Chris H. Senanayake

Published Online: 10 MAY 2012

DOI: 10.1002/9781118309872.ch1

Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective

Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective

How to Cite

Busacca, C. A., Fandrick, D. R., Song, J. J. and Senanayake, C. H. (2012) Transition Metal Catalysis in the Pharmaceutical Industry, in Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective (eds M. L. Crawley and B. M. Trost), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118309872.ch1

Editor Information

  1. 2

    Main Line Health, Berwyn, Pennsylvania, USA

  2. 3

    Stanford University, Stanford, California, USA

Author Information

  1. Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA

Publication History

  1. Published Online: 10 MAY 2012
  2. Published Print: 22 JUN 2012

ISBN Information

Print ISBN: 9780470631324

Online ISBN: 9781118309872

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Keywords:

  • pharmaceutical industry, and transition metal catalysis;
  • cross-couplings for carbon–carbon bonds;
  • transition-metal catalysis, API production;
  • academia and industry in catalysis;
  • asymmetric hydrogenation, mature catalytic technology

Summary

This chapter contains sections titled:

  • Overview of Catalysis

  • Transition Metal Catalysis in the Pharmaceutical Industry

  • Challenges in Taking Catalysis to Industrial Scales

  • Summary and Future Outlook

  • References