2. Selected Applications of Transition Metal-Catalyzed Carbon–Carbon Cross-Coupling Reactions in the Pharmaceutical Industry

  1. Matthew L. Crawley2 and
  2. Barry M. Trost3
  1. Hong C. Shen

Published Online: 10 MAY 2012

DOI: 10.1002/9781118309872.ch2

Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective

Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective

How to Cite

Shen, H. C. (2012) Selected Applications of Transition Metal-Catalyzed Carbon–Carbon Cross-Coupling Reactions in the Pharmaceutical Industry, in Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective (eds M. L. Crawley and B. M. Trost), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118309872.ch2

Editor Information

  1. 2

    Main Line Health, Berwyn, Pennsylvania, USA

  2. 3

    Stanford University, Stanford, California, USA

Author Information

  1. Department of Medicinal Chemistry, Roche R&D Center Ltd., Pudong, Shanghai, China

Publication History

  1. Published Online: 10 MAY 2012
  2. Published Print: 22 JUN 2012

ISBN Information

Print ISBN: 9780470631324

Online ISBN: 9781118309872

SEARCH

Keywords:

  • transition metal-catalyzed carbon–carbon cross-coupling;
  • carbon–carbon cross-couplings;
  • Negishi coupling and Sonogashira coupling;
  • new technology, enabling C–C cross-coupling;
  • continuous microflow synthesis

Summary

This chapter contains sections titled:

  • Introduction

  • Carbon–Carbon Cross-Couplings

  • Conclusion and Prospects

  • References