3. Selected Applications of Pd- and Cu-Catalyzed Carbon–Heteroatom Cross-Coupling Reactions in the Pharmaceutical Industry

  1. Matthew L. Crawley2 and
  2. Barry M. Trost3
  1. Jingjun Yin

Published Online: 10 MAY 2012

DOI: 10.1002/9781118309872.ch3

Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective

Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective

How to Cite

Yin, J. (2012) Selected Applications of Pd- and Cu-Catalyzed Carbon–Heteroatom Cross-Coupling Reactions in the Pharmaceutical Industry, in Applications of Transition Metal Catalysis in Drug Discovery and Development: An Industrial Perspective (eds M. L. Crawley and B. M. Trost), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118309872.ch3

Editor Information

  1. 2

    Main Line Health, Berwyn, Pennsylvania, USA

  2. 3

    Stanford University, Stanford, California, USA

Author Information

  1. Department of Process Chemistry, Merck Research Laboratories, Merck & Co., Inc., Rahway, NJ, USA

Publication History

  1. Published Online: 10 MAY 2012
  2. Published Print: 22 JUN 2012

ISBN Information

Print ISBN: 9780470631324

Online ISBN: 9781118309872

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Keywords:

  • Pd- and Cu-catalyzed carbon–heteroatom, selected applications;
  • Cu-catalyzed C–N couplings;
  • Pd- or Cu-catalyzed C–S coupling;
  • Cu-mediated oxidative boronic acid, heteroatom coupling;
  • Pd- or Cu-catalyzed C–P coupling

Summary

This chapter contains sections titled:

  • Introduction

  • Carbon-Heteroatom Cross-Couplings

  • Conclusions and Outlook

  • References