10. Respiratory Insufficiency, the Retrograde Response, and the Origin of Cancer
Published Online: 29 MAY 2012
DOI: 10.1002/9781118310311.ch10
Copyright © 2012 John Wiley & Sons, Inc.
Book Title
Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer
Additional Information
How to Cite
Seyfried, T. N. (2012) Respiratory Insufficiency, the Retrograde Response, and the Origin of Cancer, in Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118310311.ch10
Publication History
- Published Online: 29 MAY 2012
- Published Print: 8 JUN 2012
ISBN Information
Print ISBN: 9780470584927
Online ISBN: 9781118310311
- Summary
- Chapter
- References
Keywords:
- respiratory insufficiency, the RTG response and origin of cancer;
- RTG response, epigenetic for nuclear genomic stability;
- RTG response and ATP, glycolysis or glycolysis, glutamine metabolism;
- inflammation and mitochondrial LOH, respiratory damage to carcinogenesis;
- HIF-1α stability, pseudo-hypoxia, glycolytic, and respiratory insufficiency
Summary
This chapter contains sections titled:
The Retrograde (RTG) Response: An Epigenetic System Responsible for Nuclear Genomic Stability
Inflammation Injures Cellular Respiration
Hypoxia-Inducible Factor (HIF) Stability is Required for the Origin of Cancer
Mitochondria and the Mutator Phenotype
Calcium Homeostasis, Aneuploidy, and Mitochondrial Dysfunction
Mitochondrial Dysfunction and Loss of Heterozygosity (LOH)
Tissue Inflammation, Damaged Respiration, and Cancer
References