11. Mitochondria: The Ultimate Tumor Suppressor
Published Online: 29 MAY 2012
DOI: 10.1002/9781118310311.ch11
Copyright © 2012 John Wiley & Sons, Inc.
Book Title
Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer
Additional Information
How to Cite
Seyfried, T. N. (2012) Mitochondria: The Ultimate Tumor Suppressor, in Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118310311.ch11
Publication History
- Published Online: 29 MAY 2012
- Published Print: 8 JUN 2012
ISBN Information
Print ISBN: 9780470584927
Online ISBN: 9781118310311
- Summary
- Chapter
- References
Keywords:
- mitochondria, the ultimate tumor suppressor, gleaned from experimental data;
- genome instability and mitochondrial dysfunction through RTG signaling;
- normal mitochondria and malignant suppression, evidences in support;
- from rho0 cells, normal mitochondria and in vivo tumorigenesis suppression;
- normal mitochondria and Warburg reversal, when by insufficient respiration
Summary
This chapter contains sections titled:
Mitochondrial Suppression of Tumorigenicity
Normal Mitochondria Suppress Tumorigenesis in Cybrids
Evidence from rho0 Cells
Normal Mitochondria Suppress Tumorigenesis In Vivo
Normal Mouse Cytoplasm Suppresses Tumorigenic Phenotypes
Enhanced Differentiation and Suppressed Tumorigenicity in the Liver Microenvironment
Summary of Nuclear-Cytoplasmic Transfer Experiments
References