13. Metastasis
Published Online: 29 MAY 2012
DOI: 10.1002/9781118310311.ch13
Copyright © 2012 John Wiley & Sons, Inc.
Book Title
Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer
Additional Information
How to Cite
Seyfried, T. N. (2012) Metastasis, in Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118310311.ch13
Publication History
- Published Online: 29 MAY 2012
- Published Print: 8 JUN 2012
ISBN Information
Print ISBN: 9780470584927
Online ISBN: 9781118310311
- Summary
- Chapter
- References
Keywords:
- metastasis, cellular origin of metastasis, sequential;
- EMT of tumor metastasis, MET, a reexpression of epithelial features;
- myeloid hypothesis, metastatic, from myeloid, hematopoietic stem cells;
- TAM, macrophage metastasis and phagocytosis;
- fusion hybrids with dysfunctional mitochondria, and damaged respiration
Summary
This chapter contains sections titled:
Metastasis Overview
Cellular Origin of Metastasis
Macrophages and Metastasis
Carcinoma of Unknown Primary Origin
Many Metastatic Cancers Express Multiple Macrophage Properties
Linking Metastasis to Mitochondrial Dysfunction
Revisiting the “Seed and Soil” Hypothesis of Metastasis
Revisiting the Mesenchymal Epithelial Transition (MET)
Genetic Heterogeneity in Cancer Metastases
Transmissible Metastatic Cancers
The Absence of Metastases in Crown-Gall Plant Tumors
Chapter Summary
References