14. Mitochondrial Respiratory Dysfunction and the Extrachromosomal Origin of Cancer

  1. Thomas N. Seyfried

Published Online: 29 MAY 2012

DOI: 10.1002/9781118310311.ch14

Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer

Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer

How to Cite

Seyfried, T. N. (2012) Mitochondrial Respiratory Dysfunction and the Extrachromosomal Origin of Cancer, in Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118310311.ch14

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 8 JUN 2012

ISBN Information

Print ISBN: 9780470584927

Online ISBN: 9781118310311

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Keywords:

  • cancer, mitochondrial respiratory dysfunction, and extrachromosomal origin;
  • the Warburg effect, respiratory insufficiency from mitochondrial damage;
  • cancer as an epigenetic metabolic disease, connecting the links;
  • respiratory damage, oncogene expression, and genome to somatic mutations;
  • cancer histology as “red herrings,” in metabolism, due to respiratory insufficiency

Summary

This chapter contains sections titled:

  • Connecting the Links

  • Addressing the Oncogenic Paradox

  • Is Cancer Many Diseases or a Singular Disease of Energy Metabolism?

  • References