15. Nothing in Cancer Biology Makes Sense Except in the Light of Evolution

  1. Thomas N. Seyfried

Published Online: 29 MAY 2012

DOI: 10.1002/9781118310311.ch15

Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer

Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer

How to Cite

Seyfried, T. N. (2012) Nothing in Cancer Biology Makes Sense Except in the Light of Evolution, in Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118310311.ch15

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 8 JUN 2012

ISBN Information

Print ISBN: 9780470584927

Online ISBN: 9781118310311

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Keywords:

  • Nothing in Cancer Biology Makes Sense, except in the light of evolution;
  • fitness or survival in tumor cells, inconsistent with Darwin's and Potts' theory;
  • mutations, contributing to cancer progression, enhancing tumour cell fitness;
  • Nowell's hypothesis, mutability in the neoplastic, unknown;
  • mutations and genomic instability, not the cause, but on the effects

Summary

This chapter contains sections titled:

  • Revisiting Growth Advantage of Tumor Cells, Mutations, and Evolution

  • Tumor Cell Fitness in Light of the Evolutionary Theory of Rick Potts

  • Cancer Development and Lamarckian Inheritance

  • Can Teleology Explain Cancer?

  • References