17. Metabolic Management of Cancer
Published Online: 29 MAY 2012
DOI: 10.1002/9781118310311.ch17
Copyright © 2012 John Wiley & Sons, Inc.
Book Title
Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer
Additional Information
How to Cite
Seyfried, T. N. (2012) Metabolic Management of Cancer, in Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118310311.ch17
Publication History
- Published Online: 29 MAY 2012
- Published Print: 8 JUN 2012
ISBN Information
Print ISBN: 9780470584927
Online ISBN: 9781118310311
- Summary
- Chapter
- References
Keywords:
- cancer management in humans, using MET instead of the term DER;
- rational strategies, therapies targeting tumor cell energy metabolism;
- DER and tumor apoptosis, inconsistent with tumor cells as resistant to apoptosis;
- DER and proapoptotic effects, from reduced glycolytic energy;
- effective DER in tumor reduction, also to target glucose metabolism
Summary
This chapter contains sections titled:
Is it Dietary Content or Dietary Composition that Primarily Reduces Tumor Growth?
Dietary Energy Reduction and Therapeutic Fasting in Rodents and Humans
Ketogenic Diets
Glucagon and Insulin
Basal Metabolic Rate
Ketones and Glucose
Metabolic Management of Brain Cancer Using the KD
Glucose Accelerates Tumor Growth!
Glucose Regulates Blood Levels of Insulin and Insulin-Like Growth Factor 1
Dietary Energy Reduction is Antiangiogenic
Dietary Energy Reduction Targets Abnormal Tumor Vessels
Dietary Energy Reduction is Proapoptotic
Dietary Energy Reduction is Anti-Inflammatory
Targeting Energy Metabolism in Advanced Cancer
Differential Response of Normal Cells and Tumor Cells to Energy Stress
Dietary Energy Reduction is Anti-Invasive in Experimental Glioblastoma
Influence of Growth Site and Host on Tumor Progression
Implications of Dietary Energy Reduction for Anticancer Therapeutics
Targeting Glucose
Metformin
Synergistic Interaction of the Restricted Ketogenic Diet (KD-R) and 2-Deoxyglucose (2-DG)
Can Synergy Occur with the KD-R and Hyperbaric Oxygen Therapy?
Targeting Glutamine
Glutamine Targeting Inhibits Systemic Metastasis
Targeting Phagocytosis
Targeting the Microenvironment
Dietary Energy Reduction as a Mitochondrial Enhancement Therapy (MET)
Summary
References