4. Energetics of Normal Cells and Cancer Cells

  1. Thomas N. Seyfried

Published Online: 29 MAY 2012

DOI: 10.1002/9781118310311.ch4

Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer

Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer

How to Cite

Seyfried, T. N. (2012) Energetics of Normal Cells and Cancer Cells, in Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118310311.ch4

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 8 JUN 2012

ISBN Information

Print ISBN: 9780470584927

Online ISBN: 9781118310311

SEARCH

Keywords:

  • normal cell and cancer cell energetics;
  • metabolic homeostasis, energy to membrane pumps;
  • Embden–Myerhoff glycolytic pathway, glycolysis, TCA, and OxPhos;
  • glutaminolysis and cancer energy, and fate of tumor energy metabolite;
  • cancer cells on fermentation, on substrate-level phosphorylation

Summary

This chapter contains sections titled:

  • Metabolic Homeostasis

  • The Constancy of the ΔGATP

  • ATP Production in Normal Cells and Tumor Cells

  • Energy Production Through Glucose Fermentation

  • Glutaminolysis with or without Lactate Production

  • Transamination Reactions

  • TCA Cycle, Substrate-Level Phosphorylation

  • Cholesterol Synthesis and Hypoxia

  • Summary

  • References