5. Respiratory Dysfunction in Cancer Cells

  1. Thomas N. Seyfried

Published Online: 29 MAY 2012

DOI: 10.1002/9781118310311.ch5

Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer

Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer

How to Cite

Seyfried, T. N. (2012) Respiratory Dysfunction in Cancer Cells, in Cancer as a Metabolic Disease: On the Origin, Management and Prevention of Cancer, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118310311.ch5

Publication History

  1. Published Online: 29 MAY 2012
  2. Published Print: 8 JUN 2012

ISBN Information

Print ISBN: 9780470584927

Online ISBN: 9781118310311

SEARCH

Keywords:

  • respiratory dysfunction in cancer cells;
  • Bayley and Devilee on aerobic glycolysis (Warburg), and the respiratory injury;
  • respiratory insufficiency, oncogene, tumor suppressor gene defects;
  • respiratory efficiency and CL, abnormal energy metabolism in tumor cells;
  • normal cells and cancer cells, and respiration differences

Summary

This chapter contains sections titled:

  • Normal Mitochondria

  • Morphological Defects in Tumor Cell Mitochondria

  • Proteomic Abnormalities in Tumor Cell Mitochondria

  • Lipidomic Abnormalities in Tumor Cell Mitochondria

  • Cardiolipin: A Mitochondrial-Specific Lipid

  • Cardiolipin and Abnormal Energy Metabolism in Tumor Cells

  • Complicating Influence of the In Vitro Growth Environment on Cardiolipin Composition and Energy Metabolism

  • Mitochondrial Uncoupling and Cancer

  • Cancer Cell Heat Production and Uncoupled Mitochondria

  • Personal Perspective

  • Summary

  • References