19. Autoimmune Hepatitis in Adults and Children

  1. E. Jenny Heathcote MB, BS, MD, FRCP, FRCP(C)3,4,5,6
  1. Gideon M. Hirschfield MB, BChir, MRCP, PhD1,2,4

Published Online: 4 SEP 2012

DOI: 10.1002/9781118314968.ch19

Hepatology: Diagnosis and Clinical Management

Hepatology: Diagnosis and Clinical Management

How to Cite

Hirschfield, G. M. (2012) Autoimmune Hepatitis in Adults and Children, in Hepatology: Diagnosis and Clinical Management (ed E. J. Heathcote), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118314968.ch19

Editor Information

  1. 3

    Francis Family Chair in Hepatology Research, Toronto, Ontario, Canada

  2. 4

    University of Toronto, Toronto, Ontario, Canada

  3. 5

    Patient Based Clinical Research Division, Toronto Western Research Institute, Toronto, Ontario, Canada

  4. 6

    University Health Network/Toronto Western Hospital, Toronto, Ontario, Canada

Author Information

  1. 1

    Liver Centre, Division of Gastroenterology, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada

  2. 2

    Centre for Liver Research, University of Birmingham, Birmingham, UK

  3. 4

    University of Toronto, Toronto, Ontario, Canada

Publication History

  1. Published Online: 4 SEP 2012
  2. Published Print: 12 OCT 2012

ISBN Information

Print ISBN: 9780470656174

Online ISBN: 9781118314968

SEARCH

Keywords:

  • autoimmune hepatitis;
  • prednisone;
  • azathioprine;
  • antinuclear antibody;
  • smooth muscle antibody

Summary

Autoimmune hepatitis is an uncommon disease, which is encountered in patients of all ages. Fortunately, it is a treatment-responsive hepatitis. There is no single diagnostic test, and clinical acumen is required to accurately diagnose patients and to treat them appropriately with immunosuppressive agents. Long-term follow-up is essential for both surveillance of the consequences of chronic liver disease and the sideeffects of immunosuppression, being best carried out by a physician with an interest in liver disease.