26. Problems in Pediatrics

  1. C. J. Hawkey FMedSci2,
  2. Jaime Bosch MD, PhD3,4,
  3. Joel E. Richter MD, FACP, MACG5,6,
  4. Guadalupe Garcia-Tsao MD7,8 and
  5. Francis K. L. Chan MD9
  1. Simon Murch PhD, FRCP, FRCPCH

Published Online: 16 APR 2012

DOI: 10.1002/9781118321386.ch26

Textbook of Clinical Gastroenterology and Hepatology, Second Edition

Textbook of Clinical Gastroenterology and Hepatology, Second Edition

How to Cite

Murch, S. (2012) Problems in Pediatrics, in Textbook of Clinical Gastroenterology and Hepatology, Second Edition (eds C. J. Hawkey, J. Bosch, J. E. Richter, G. Garcia-Tsao and F. K. L. Chan), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118321386.ch26

Editor Information

  1. 2

    Nottingham Digestive Diseases Centre, University of Nottingham and Nottingham University Hospitals, Nottingham, UK

  2. 3

    Hepatic Hemodynamic Laboratory, Liver Unit Hospital Clínic-IDIBAPS, University of Barcelona, Spain

  3. 4

    Biomedical Research Centre Network of Hepatic and Digestive Diseases (CIBERehd), National Institute of Health Carlos III Ministry of Science and Innovation Barcelona, Spain

  4. 5

    Division of Gastroenterology and Nutrition, University of South Florida Tampa, FL, USA

  5. 6

    Joy M. Culverhouse Center for Esophageal Diseases, University of South Florida Tampa, FL, USA

  6. 7

    Section of Digestive Diseases Yale University, School of Medicine New Haven, CT, USA

  7. 8

    Veterans Affairs Connecticut Healthcare System West Haven, CT, USA

  8. 9

    Department of Medicine & Therapeutics The Chinese University of Hong Kong, Hong Kong SAR, China

Author Information

  1. Division of Metabolic and Vascular Health, Warwick Medical School, The University of Warwick, Coventry, UK

Publication History

  1. Published Online: 16 APR 2012
  2. Published Print: 20 APR 2012

ISBN Information

Print ISBN: 9781405191821

Online ISBN: 9781118321386



  • Child;
  • Gastroesophageal reflux;
  • Constipation;
  • Celiac disease;
  • Inflammatory bowel disease;
  • Necrotising enterocolitis;
  • Food allergy;
  • Intractable diarrhea;
  • Autoimmune enteropathy


Some gastrointestinal problems (e.g. constipation, gastroesophageal reflux, Celiac disease, intestinal food allergy, IBD) are now relatively common in pediatric gastroenterological practice. Patterns of disease are, however, changing and there is increasing recognition that food allergic responses may affect intestinal motility. An increase in preterm deliveries has led to a greater incidence of neonatal necrotizing enterocolitis. There has been recent advance in understanding the rare congenital disorders causing intractable diarrhea and autoimmune enteropathy, suggesting the potential for genetic therapy.