5. Nutrition, Protein Turnover and Muscle Mass

  1. Alfonso J. Cruz-Jentoft4 and
  2. John E. Morley5,6
  1. Stéphane Walrand1,2,
  2. Christelle Guillet1,2 and
  3. Yves Boirie1,2,3

Published Online: 27 JUL 2012

DOI: 10.1002/9781118338032.ch5



How to Cite

Walrand, S., Guillet, C. and Boirie, Y. (2012) Nutrition, Protein Turnover and Muscle Mass, in Sarcopenia (eds A. J. Cruz-Jentoft and J. E. Morley), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118338032.ch5

Editor Information

  1. 4

    Servicio de Geriatría, Hospital Universitario Ramón y Cajal, Madrid, Spain

  2. 5

    Division of Geriatric Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA

  3. 6

    Division of Endocrinology, Saint Louis University School of Medicine, St. Louis, MO, USA

Author Information

  1. 1

    Clermont Université, Université d'Auvergne, Unité de Nutrition Humaine, Clermont-Ferrand, France

  2. 2

    INRA, UNH, CRNH Auvergne, Clermont-Ferrand, France

  3. 3

    CHU Clermont-Ferrand, Service de Nutrition Clinique, Clermont-Ferrand, France

Publication History

  1. Published Online: 27 JUL 2012
  2. Published Print: 30 AUG 2012

ISBN Information

Print ISBN: 9781119975878

Online ISBN: 9781118338032



  • nutrition, protein turnover and muscle mass;
  • muscle erosion after 55, factors for disability in the elderly;
  • sarcopenia, with age, differentiated from cachexia;
  • sarcopenia and skeletal fiber atrophy, of type II fibers;
  • age-related loss of muscle proteins, protein synthesis/degradation;
  • the elderly, skeletal muscle ‘Anabolic resistance’ to nutrition;
  • hormones and muscle sensitivity, muscle protein threshold;
  • age-related anabolic resistance, overcome by amino acids;
  • RE anabolic effect, dietary on muscle protein synthesis;
  • muscle mass loss/and muscle/CNS/humoral/lifestyle changes


This chapter contains sections titled:

  • Introduction

  • Evidences for a Role for Nutrition in Sarcopenia

  • Anabolic Response to Physical Exercise in the Elderly

  • Combination of Nutritional and Training Strategies

  • Concluding Remarks and Future Direction

  • References