18. Transfusion Medicine

  1. Petra Seeber MD1 and
  2. Aryeh Shander MD, FCCM, FCCP2,3

Published Online: 4 JUL 2012

DOI: 10.1002/9781118338070.ch18

Basics of Blood Management, Second edition

Basics of Blood Management, Second edition

How to Cite

Seeber, P. and Shander, A. (2012) Transfusion Medicine, in Basics of Blood Management, Second edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118338070.ch18

Author Information

  1. 1

    Institute for Blood Management, Gotha, Germany

  2. 2

    Critical Care Medicine and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ, USA

  3. 3

    Mount Sinai School of Medicine, Mount Sinai Hospital, New York, NY, USA

Publication History

  1. Published Online: 4 JUL 2012
  2. Published Print: 24 AUG 2012

ISBN Information

Print ISBN: 9780470670705

Online ISBN: 9781118338070



  • Transfusion;
  • History;
  • Storage lesions;
  • Proteomics;
  • Transfusion-associated risks;
  • Benefits of transfusions;
  • Transfusion guidelines;
  • Decision-making;
  • Immunomodulation;
  • Clinical effects


Transfusion of blood or its main components (plasma, platelets, red cells, or white cells) is one of the most widely used therapeutic options. Transfusions are available in the remotest parts of the world, even where there are no other basic medical facilities. Its use is mostly guided by emotion and peer pressure, rather than by science. This chapter will introduce the commonly available blood products. Then it outlines an evidence-based approach to the decision to transfuse or not to transfuse, considering what is (or is not) known about the benefits of transfusions, associated risks, alternatives, and effects of doing nothing. It will conclude with a look at current transfusion guidelines.