6. Fluid Management

  1. Petra Seeber MD1 and
  2. Aryeh Shander MD, FCCM, FCCP2,3

Published Online: 4 JUL 2012

DOI: 10.1002/9781118338070.ch6

Basics of Blood Management, Second edition

Basics of Blood Management, Second edition

How to Cite

Seeber, P. and Shander, A. (2012) Fluid Management, in Basics of Blood Management, Second edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118338070.ch6

Author Information

  1. 1

    Institute for Blood Management, Gotha, Germany

  2. 2

    Critical Care Medicine and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ, USA

  3. 3

    Mount Sinai School of Medicine, Mount Sinai Hospital, New York, NY, USA

Publication History

  1. Published Online: 4 JUL 2012
  2. Published Print: 24 AUG 2012

ISBN Information

Print ISBN: 9780470670705

Online ISBN: 9781118338070



  • Fluid resuscitation;
  • Plasma substitute;
  • Crystalloids;
  • Colloids;
  • Volume therapy;
  • Hypertonic resuscitation;
  • Balanced solution;
  • Hypotensive resuscitation


Circulating intravascular volume is essential for survival. Therefore, fluid resuscitation is one of the first therapeutic measures in patients with hypovolemia of various etiologies. The choice of resuscitation fluids itself may have an influence on the outcome, but is the subject of heated debate. Some physicians prefer unbalanced or balanced crystalloids such as normal saline or Ringer's solution, others colloids such as hydroxyethyl starch, gelatin or dextran, and others a combination of both, with or without hypertonic fluids. Differences in the influence of the resuscitation fluids on the microvasculature, coagulation profile, rheology, electrolyte and water balance, and other variables may make one specific fluid more suitable in a certain situation than another fluid. This chapter gives an overview of resuscitation fluids and how they can be used to the greatest benefit in blood management.