9. Artificial Blood

  1. Petra Seeber MD1 and
  2. Aryeh Shander MD, FCCM, FCCP2,3

Published Online: 4 JUL 2012

DOI: 10.1002/9781118338070.ch9

Basics of Blood Management, Second edition

Basics of Blood Management, Second edition

How to Cite

Seeber, P. and Shander, A. (2012) Artificial Blood, in Basics of Blood Management, Second edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118338070.ch9

Author Information

  1. 1

    Institute for Blood Management, Gotha, Germany

  2. 2

    Critical Care Medicine and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ, USA

  3. 3

    Mount Sinai School of Medicine, Mount Sinai Hospital, New York, NY, USA

Publication History

  1. Published Online: 4 JUL 2012
  2. Published Print: 24 AUG 2012

ISBN Information

Print ISBN: 9780470670705

Online ISBN: 9781118338070



  • Hemoglobin-based oxygen carrier;
  • Perfluorocarbons;
  • Artificial oxygen carrier;
  • Artificial platelet substitute;
  • Anemia;
  • Hemorrhagic shock;
  • History


Recreating blood, the fluid of life, is a human dream that dates back thousands of years. However, myth and reality met when the first unsuccessful attempts were made to actually resuscitate patients. From the humble beginnings up to this day it has not been possible to even come close to recreating one of the main blood components, let alone whole blood. However, as the result of decades of research, several drugs have been developed that are able to mimic some of the properties of blood components. This chapter will give an overview of science's quest to recreate the fluid of life.