19. Biovigilance in the United States

  1. René R. P. De Vries MD5 and
  2. Jean-Claude Faber MD6
  1. D. Michael Strong PhD1,
  2. Barbee Whitaker PhD2,
  3. Matthew J. Kuehnert MD3 and
  4. Jerry A. Holmberg PhD4

Published Online: 6 AUG 2012

DOI: 10.1002/9781118338179.ch19

Hemovigilance: An Effective Tool for Improving Transfusion Safety

Hemovigilance: An Effective Tool for Improving Transfusion Safety

How to Cite

Strong, D. M., Whitaker, B., Kuehnert, M. J. and Holmberg, J. A. (2012) Biovigilance in the United States, in Hemovigilance: An Effective Tool for Improving Transfusion Safety (eds R. R. P. De Vries and J.-C. Faber), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118338179.ch19

Editor Information

  1. 5

    Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands

  2. 6

    Blood Transfusion Service of the Luxembourg Red Cross, Luxembourg

Author Information

  1. 1

    Department of Orthopaedics and Sports Medicine, University of Washington School of Medicine, Seattle, WA, USA

  2. 2

    Data and Special Programs AABB Bethesda, MD, USA

  3. 3

    Organ, and other Tissue Safety, Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA

  4. 4

    Scientific Affairs, Novartis Vaccines and Diagnostics Inc., Emeryville, CA, USA

Publication History

  1. Published Online: 6 AUG 2012
  2. Published Print: 29 AUG 2012

ISBN Information

Print ISBN: 9780470655276

Online ISBN: 9781118338179



  • biovigilance in the United States;
  • US, voluntary/mandatory reporting, patchwork for biovigilance;
  • mandatory reporting to federal government, through FDA;
  • task-force working groups, infrastructure/content for blood transfusion;
  • transfusion recipient surveillance;
  • blood donation surveillance;
  • TTSN;
  • data, capturing information about donor/donation/reaction


This chapter contains sections titled:

  • History of biovigilance development

  • Transfusion recipient surveillance

  • Blood donation surveillance

  • Transplantation Transmission Sentinel Network (TTSN)

  • The future of biovigilance in the US

  • Acknowledgement

  • References