13. The Role of Cholesterol and Lipid Rafts in Regulation of TLR Receptors

  1. Irena Levitan2 and
  2. Francisco J. Barrantes3
  1. Ruxana T. Sadikot

Published Online: 22 JUN 2012

DOI: 10.1002/9781118342312.ch13

Cholesterol Regulation of Ion Channels and Receptors

Cholesterol Regulation of Ion Channels and Receptors

How to Cite

Sadikot, R. T. (2012) The Role of Cholesterol and Lipid Rafts in Regulation of TLR Receptors, in Cholesterol Regulation of Ion Channels and Receptors (eds I. Levitan and F. J. Barrantes), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118342312.ch13

Editor Information

  1. 2

    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA

  2. 3

    Facultad de Ciencias Médicas, Pontificia Universidad Católica Argentina, Aires, Argentina

Author Information

  1. University of Illinois at Chicago, Chicago, IL, USA

Publication History

  1. Published Online: 22 JUN 2012
  2. Published Print: 16 JUL 2012

ISBN Information

Print ISBN: 9780470874325

Online ISBN: 9781118342312

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Keywords:

  • cholesterol and lipid raft role in TLR receptor regulation;
  • host defense protective ability and PRRs;
  • PAMP recognition by TLRs, transcriptional upregulation of distinct genes;
  • TLRs in innate immune response, lipid rafts and TLR signaling;
  • TLRs, and N-terminal LPRs, TLRs and protein localization in raft domains

Summary

This chapter contains sections titled:

  • Toll-Like Receptor Signaling

  • Lipid Rafts and TLR Signaling

  • Summary

  • References