5. Cholesterol Regulation of Cardiac Ion Channels

  1. Irena Levitan4 and
  2. Francisco J. Barrantes5
  1. Elise Balse1,2,
  2. Stéphane Hatem1,2 and
  3. Stanley Nattel3

Published Online: 22 JUN 2012

DOI: 10.1002/9781118342312.ch5

Cholesterol Regulation of Ion Channels and Receptors

Cholesterol Regulation of Ion Channels and Receptors

How to Cite

Balse, E., Hatem, S. and Nattel, S. (2012) Cholesterol Regulation of Cardiac Ion Channels, in Cholesterol Regulation of Ion Channels and Receptors (eds I. Levitan and F. J. Barrantes), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118342312.ch5

Editor Information

  1. 4

    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA

  2. 5

    Facultad de Ciencias Médicas, Pontificia Universidad Católica Argentina, Aires, Argentina

Author Information

  1. 1

    Faculté de médecine Pitié-Salpétrière, INSERM UMRS-956, Paris, France

  2. 2

    Université Pierre et Marie Curie, Sorbonne Universités, Paris, France

  3. 3

    Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada

Publication History

  1. Published Online: 22 JUN 2012
  2. Published Print: 16 JUL 2012

ISBN Information

Print ISBN: 9780470874325

Online ISBN: 9781118342312

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Keywords:

  • cardiac ion channel cholesterol regulation, regulating channel traffic;
  • cholesterol on cardiac excitability, membrane cholesterol and cardiac repolarization;
  • lipid interplay, plasma membrane and channel function, in surface expression;
  • ion channel trafficking components, and cholesterol changes;
  • cholesterol-dependent function alteration, and therapeutic potential

Summary

This chapter contains sections titled:

  • Introduction

  • Effect of Cholesterol on Cardiac Excitability

  • Mechanisms of Cholesterol Effects on Ion Channels

  • Cholesterol as a Target for Therapeutic Agents

  • References