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15. Target-Oriented and Diversity-Oriented Organic Synthesis

  1. Janine Cossy,
  2. Stellios Arseniyadis
  1. Raphaël Rodriguez

Published Online: 30 AUG 2012

DOI: 10.1002/9781118342886.ch15

Modern Tools for the Synthesis of Complex Bioactive Molecules

Modern Tools for the Synthesis of Complex Bioactive Molecules

How to Cite

Rodriguez, R. (2012) Target-Oriented and Diversity-Oriented Organic Synthesis, in Modern Tools for the Synthesis of Complex Bioactive Molecules (eds J. Cossy and S. Arseniyadis), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118342886.ch15

Editor Information

  1. Laboratoire de Chimie Organique, UMR 7084 CNRS ESPCI, ParisTech, Paris, France

Author Information

  1. Department of Chemistry, Cambridge University, Cambridge, United Kingdom

Publication History

  1. Published Online: 30 AUG 2012
  2. Published Print: 21 SEP 2012

ISBN Information

Print ISBN: 9780470616185

Online ISBN: 9781118342886

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Keywords:

  • target-oriented and diversity-oriented organic synthesis;
  • DOS, biologically active and associated cellular mechanisms;
  • scope of biased and unbiased approaches;
  • scope of DOS, structural complexity and molecular diversity;
  • chemoselective reactions used in DOS

Summary

This chapter contains sections titled

  • Introduction

  • Target-Oriented and Diversity-Oriented Synthesis

  • Alternative Approaches to Identifying Biologically Active Small Molecules

  • Strategies to Create Structurally Complex and Diverse Small Molecules

  • Recent Examples of Chemoselective Reactions Used in DOS

  • Biologically Active Small Molecules Obtained from DOS

  • Perspectives

  • Abbreviations

  • References