20. Spinal Cord Stimulation in Complex Regional Pain Syndrome

  1. Sam Eljamel3 and
  2. Konstantin V. Slavin4
  1. Eduardo Goellner1 and
  2. Konstantin V. Slavin2

Published Online: 19 JUL 2013

DOI: 10.1002/9781118346396.ch20

Neurostimulation: Principles and Practice

Neurostimulation: Principles and Practice

How to Cite

Goellner, E. and V. Slavin, K. (2013) Spinal Cord Stimulation in Complex Regional Pain Syndrome, in Neurostimulation: Principles and Practice (eds S. Eljamel and K. V. Slavin), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118346396.ch20

Editor Information

  1. 3

    Centre for Neurosciences, Ninewells Hospital & Medical School, Dundee, Scotland, UK

  2. 4

    Department of Neurosurgery, University of Illinois at Chicago. Chicago, Illinois, USA

Author Information

  1. 1

    Hospital Mãe de Deus, Porto Alegre/RS, Brazil

  2. 2

    University of Illinois at Chicago, Illinois, Chicago, USA

Publication History

  1. Published Online: 19 JUL 2013
  2. Published Print: 19 AUG 2013

ISBN Information

Print ISBN: 9781118346358

Online ISBN: 9781118346396



  • complex regional pain syndrome (CRPS);
  • neurostimulation;
  • spinal cord stimulation (SPS)


Complex regional pain syndrome (CRPS) is a neuropathic disorder characterized by continuous pain that is disproportionate to the inciting event and is associated with trophic changes and functional impairment. Spinal cord stimulation (SCS) has been shown to be effective in different chronic pain conditions and is an important option for the treatment of refractory CRPS. This chapter provides a list of diagnostic criteria for CRPS based on the modified International Association for the Study of Pain (IASP) classification, and discusses the rationale of SCS in CRPS. SCS has been used for the treatment of CRPS for decades in thousands of patients. Taking into consideration economical aspects, SCS seems to be cost‐effective in the long‐term compared with conventional treatment alone. Hardware‐related problems such as migration of the lead, and pulse generator malfunction, are some of potential, but easily solvable, side effects related to SCS and CRPS.