22. Peripheral Nerve Stimulation in Head and Face Pain

  1. Sam Eljamel3 and
  2. Konstantin V. Slavin4
  1. Konstantin V. Slavin1,
  2. Serge Y. Rasskazoff2 and
  3. Sami Al-Nafi1

Published Online: 19 JUL 2013

DOI: 10.1002/9781118346396.ch22

Neurostimulation: Principles and Practice

Neurostimulation: Principles and Practice

How to Cite

Slavin, K. V., Rasskazoff, S. Y. and Al-Nafi, S. (2013) Peripheral Nerve Stimulation in Head and Face Pain, in Neurostimulation: Principles and Practice (eds S. Eljamel and K. V. Slavin), John Wiley & Sons, Ltd, Oxford, UK. doi: 10.1002/9781118346396.ch22

Editor Information

  1. 3

    Centre for Neurosciences, Ninewells Hospital & Medical School, Dundee, Scotland, UK

  2. 4

    Department of Neurosurgery, University of Illinois at Chicago. Chicago, Illinois, USA

Author Information

  1. 1

    University of Illinois at Chicago, Chicago, Illinois, USA

  2. 2

    Flint, Michigan, USA

Publication History

  1. Published Online: 19 JUL 2013
  2. Published Print: 19 AUG 2013

ISBN Information

Print ISBN: 9781118346358

Online ISBN: 9781118346396



  • chronic headaches;
  • face pain;
  • occipital neuralgia (ON);
  • peripheral nerve stimulation (PNS);
  • trigeminal neuropathic pain (TNP)


Peripheral nerve stimulation (PNS) refers to electrical neuromodulation that involves delivery of repetitive low‐power electrical impulses directly to the fibers of a peripheral nerve. Today, PNS is an established modality in the spectrum of neuromodulation for pain: it is an important part of the neuromodulation continuum that starts from peripheral nerve endings and ends in somatosensory, motor, and limbic cortical areas. The most established indication for craniofacial PNS is occipital neuralgia (ON), a chronic pain syndrome characterized by stabbing sharp pains in the distribution of the occipital nerve(s). Trigeminal neuropathic pain (TNP) represents a chronic pain syndrome that combines sharp or dull pain in the distribution of one or several branches of the trigeminal nerve and usually involves a combination of constant and episodic pain. Finally, there is a major shortage of well‐designed prospective studies that could validate the value of PNS and document its clinical efficacy and safety.