12. Depression and Movement Disorders

  1. Andres M. Kanner MD4,5,6
  1. Oliver Tüscher MD1,2,3 and
  2. Ludger Tebartz van Elst MD1,2

Published Online: 4 JUL 2012

DOI: 10.1002/9781118348093.ch12

Depression in Neurologic Disorders: Diagnosis and Management

Depression in Neurologic Disorders: Diagnosis and Management

How to Cite

Tüscher, O. and Tebartz van Elst, L. (2012) Depression and Movement Disorders, in Depression in Neurologic Disorders: Diagnosis and Management (ed A. M. Kanner), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118348093.ch12

Editor Information

  1. 4

    Departments of Neurological Sciences and Psychiatry, Rush Medical College at Rush University, Chicago, IL, USA

  2. 5

    Laboratory of EEG and Video-EEG-Telemetry, Chicago, IL, USA

  3. 6

    Section of Epilepsy and Rush Epilepsy Center, Rush University Medical Center, Chicago, IL, USA

Author Information

  1. 1

    Section of Experimental Neuropsychiatry and Psychotherapy, Department of Psychiatry and Psychotherapy, Germany

  2. 2

    Department of Neurology, University of Freiburg Medical Center, Freiburg, Germany

  3. 3

    Department of Psychiatry and Psychotherapy, University of Mainz Medical Center, Mainz, Germany

Publication History

  1. Published Online: 4 JUL 2012
  2. Published Print: 24 AUG 2012

ISBN Information

Print ISBN: 9781444330588

Online ISBN: 9781118348093



  • depression;
  • anxiety;
  • movement disorders;
  • Parkinson's disease;
  • Huntington's disease;
  • neuropsychiatry


Movement disorders have long been perceived solely as disorders of the motor system. The improvement of motor symptom therapy, the rise of modern neuroimaging techniques, and the development of new therapies such as deep brain stimulation have reinstated the view of movement disorders as complex neurobehavioral syndromes. Among the behavioral symptoms, depressive symptoms are the most prevalent, affecting 30–50% of all patients with movement disorder. Depression is also one of the most disabling factors in movement disorders, heavily impacting the quality of life of patients and caregivers. Despite its importance, depression in movement disorders is still often underestimated, underdiagnosed, and undertreated. This chapter discusses the prevalence, diagnostic assessment, clinical characteristics, pathophysiology, and therapy of depression in two exemplary movement disorders: Parkinson's and Huntington's disease.