15. Depression and Traumatic Brain Injury

  1. Andres M. Kanner MD3,4,5
  1. Seth A. Mensah MB, ChB, DPM, MSc, MRCPsych1 and
  2. Michael P. Kerr MD2

Published Online: 4 JUL 2012

DOI: 10.1002/9781118348093.ch15

Depression in Neurologic Disorders: Diagnosis and Management

Depression in Neurologic Disorders: Diagnosis and Management

How to Cite

Mensah, S. A. and Kerr, M. P. (2012) Depression and Traumatic Brain Injury, in Depression in Neurologic Disorders: Diagnosis and Management (ed A. M. Kanner), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118348093.ch15

Editor Information

  1. 3

    Departments of Neurological Sciences and Psychiatry, Rush Medical College at Rush University, Chicago, IL, USA

  2. 4

    Laboratory of EEG and Video-EEG-Telemetry, Chicago, IL, USA

  3. 5

    Section of Epilepsy and Rush Epilepsy Center, Rush University Medical Center, Chicago, IL, USA

Author Information

  1. 1

    Consultant Neuropsychiatrist, Welsh Neuropsychiatry Service, Whitchurch Hospital, Cardiff, UK

  2. 2

    Welsh Centre for Learning Disabilities, Cardiff University, Cardiff, UK

Publication History

  1. Published Online: 4 JUL 2012
  2. Published Print: 24 AUG 2012

ISBN Information

Print ISBN: 9781444330588

Online ISBN: 9781118348093



  • traumatic brain injury;
  • depression;
  • assessment;
  • classification;
  • diagnosis;
  • cerebrovascular disease;
  • quality of life;
  • outcome;
  • suicide;
  • treatment


A considerable body of research has identified the importance of depression as a comorbidity associated with traumatic brain injury. This comorbidity may lead to poorer quality of life and increased suicide risk, although suicide in particular is influenced by premorbid personality. The symptomatology of posttraumatic epilepsy can be mistaken for features of brain injury, such as apathy and lack of drive. It appears that treatment options are similar to those of depression in the general population. Adequate and prompt identification and treatment of depression in people with traumatic brain injury may ameliorate the impact of the injury on an individual's quality of life.