5. Suicidality in Neurologic Diseases

  1. Andres M. Kanner MD2,3,4
  1. Yukari Tadokoro1 and
  2. Andres M. Kanner MD2,3,4

Published Online: 4 JUL 2012

DOI: 10.1002/9781118348093.ch5

Depression in Neurologic Disorders: Diagnosis and Management

Depression in Neurologic Disorders: Diagnosis and Management

How to Cite

Tadokoro, Y. and Kanner, A. M. (2012) Suicidality in Neurologic Diseases, in Depression in Neurologic Disorders: Diagnosis and Management (ed A. M. Kanner), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118348093.ch5

Editor Information

  1. 2

    Departments of Neurological Sciences and Psychiatry, Rush Medical College at Rush University, Chicago, IL, USA

  2. 3

    Laboratory of EEG and Video-EEG-Telemetry, Chicago, IL, USA

  3. 4

    Section of Epilepsy and Rush Epilepsy Center, Rush University Medical Center, Chicago, IL, USA

Author Information

  1. 1

    Department of Neuropsychiatry, School of Medicine, Aichi Medical University, Aichi-ken, Japan

  2. 2

    Departments of Neurological Sciences and Psychiatry, Rush Medical College at Rush University, Chicago, IL, USA

  3. 3

    Laboratory of EEG and Video-EEG-Telemetry, Chicago, IL, USA

  4. 4

    Section of Epilepsy and Rush Epilepsy Center, Rush University Medical Center, Chicago, IL, USA

Publication History

  1. Published Online: 4 JUL 2012
  2. Published Print: 24 AUG 2012

ISBN Information

Print ISBN: 9781444330588

Online ISBN: 9781118348093

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Keywords:

  • major depressive disorder;
  • bipolar disorder;
  • generalized anxiety disorder;
  • completed suicide;
  • suicidal behavior;
  • suicidal ideation

Summary

Suicidality is a relatively frequent complication of most major neurologic disorders, including stroke, epilepsy, multiple sclerosis, migraine, Huntington's disease, amyotrophic lateral sclerosis, and traumatic and spinal cord injury. In some neurologic conditions like epilepsy, suicide accounts for up to 15% of all deaths.

The presence of comorbid psychiatric disorders, in particular major depressive and generalized anxiety disorder occurring together, can be among the leading risk factors for suicidality in patients with neurologic disorders. Thus, screening for these conditions can facilitate the detection of patients at risk for suicidal behavior. In this chapter, we review the epidemiologic aspects, pathogenic mechanisms, and clinical manifestations of suicidality in the major neurologic disorders.