10. miRNAs in Human Prostate Cancer

  1. Saura C. Sahu
  1. Ernest K. Amankwah1 and
  2. Jong Y. Park1,2

Published Online: 8 AUG 2012

DOI: 10.1002/9781118349045.ch10

Toxicology and Epigenetics

Toxicology and Epigenetics

How to Cite

Amankwah, E. K. and Park, J. Y. (2012) miRNAs in Human Prostate Cancer, in Toxicology and Epigenetics (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118349045.ch10

Editor Information

  1. Division of Toxicology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, Laurel, Maryland, USA

Author Information

  1. 1

    Division of Cancer Prevention and Control, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA

  2. 2

    College of Medicine, University of Florida, FL, USA

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 7 SEP 2012

ISBN Information

Print ISBN: 9781119976097

Online ISBN: 9781118349045



  • miRNAs in human prostate cancer;
  • role of microRNAs (miRNAs) in prostate cancer;
  • biogenesis, function, target of miRNAs, role of miRNAs in cancer;
  • secondary structures of mRNA, and target recognition site;
  • miRNAs, critical functions in gene expression/dysregulation in tumorigenesis;
  • miRNAs as oncogenes and tumor suppressors;
  • tumor-suppressive role of miRNAs in prostate cancer, in cell migration/invasion;
  • miRNA expression studies on human prostate tumor samples


This chapter contains sections titled:

  • Introduction

  • Biogenesis, function, and target of miRNA

  • miRNA and human cancer

  • miRNAs as oncogenes and tumor suppressors

  • Expression profile of miRNA in prostate cancer

  • miRNA as therapeutic targets for prostate cancer

  • Conclusion and future directions

  • References