15. Nuclear RNA Silencing and Related Phenomena in Animals

  1. Saura C. Sahu
  1. Radek Malik and
  2. Petr Svoboda

Published Online: 8 AUG 2012

DOI: 10.1002/9781118349045.ch15

Toxicology and Epigenetics

Toxicology and Epigenetics

How to Cite

Malik, R. and Svoboda, P. (2012) Nuclear RNA Silencing and Related Phenomena in Animals, in Toxicology and Epigenetics (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118349045.ch15

Editor Information

  1. Division of Toxicology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, Laurel, Maryland, USA

Author Information

  1. Institute of Molecular Genetics, Czech Academy of Sciences, Prague, Czech Republic

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 7 SEP 2012

ISBN Information

Print ISBN: 9781119976097

Online ISBN: 9781118349045



  • nuclear RNA silencing, and related phenomena in animals;
  • RNA silencing, small RNAs functioning as sequence-specific guides;
  • knowledge, of nuclear RNA silencing in mammals;
  • complexity of RNA silencing, lower in mammals;
  • mammalian Dicer-generated small RNAs, in mammalian cells, miRNAs;
  • miRNA-mediated transcriptional regulation;
  • RNA silencing and RIGS in mammals, having no links;
  • silencing effect, unquestionable, small RNAs sequences in gene silence


This chapter contains sections titled:

  • Introduction

  • Conclusion

  • Acknowledgments

  • References