21. Nanoparticles and Toxicoepigenomics

  1. Saura C. Sahu
  1. Manasi P. Jain,
  2. Angela O. Choi and
  3. Dusica Maysinger

Published Online: 8 AUG 2012

DOI: 10.1002/9781118349045.ch21

Toxicology and Epigenetics

Toxicology and Epigenetics

How to Cite

Jain, M. P., Choi, A. O. and Maysinger, D. (2012) Nanoparticles and Toxicoepigenomics, in Toxicology and Epigenetics (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118349045.ch21

Editor Information

  1. Division of Toxicology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, Laurel, Maryland, USA

Author Information

  1. Department of Pharmacology and Therapeutics, McGill University, Montreal, Canada

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 7 SEP 2012

ISBN Information

Print ISBN: 9781119976097

Online ISBN: 9781118349045



  • nanoparticles and toxicoepigenomics, therapeutic/deleterious;
  • atomic/molecular in nanotechnology engineering;
  • nanoparticles, from 1 to 100 nm in size;
  • nanosize range, affecting physical-chemical of nanoparticles;
  • naturally occurring NPs, UFPs, and synthetic engineered;
  • engineered synthetic NPs, as QDs, micelles, CNTs, fullerenes;
  • ambient UFPs/engineered, threat of NPs in water/aquatic life;
  • enhanced stability/optimized properties of NPs, in drug delivery/imaging;
  • NP toxicity/nanotoxicology, cellular events in NP response


This chapter contains sections titled:

  • Nanoparticles

  • Particles and the environment

  • Nanoparticles in soil

  • Nanoparticles in water

  • Nanoparticles in air

  • Nanoparticles in medicine

  • Nanotoxicology

  • Nanotoxicology in humans and experimental animals

  • Complications with nanotoxicological studies

  • Molecular mechanisms of nanoparticle toxicity and cellular defense mechanisms

  • Molecular mechanisms of nanoparticle-induced cytotoxicity

  • Nano-epigenomcs and epigenetics

  • Conclusion

  • References