23. Transcriptomics: Applications in Epigenetic Toxicology

  1. Saura C. Sahu
  1. Pius Joseph

Published Online: 8 AUG 2012

DOI: 10.1002/9781118349045.ch23

Toxicology and Epigenetics

Toxicology and Epigenetics

How to Cite

Joseph, P. (2012) Transcriptomics: Applications in Epigenetic Toxicology, in Toxicology and Epigenetics (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118349045.ch23

Editor Information

  1. Division of Toxicology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, Laurel, Maryland, USA

Author Information

  1. Molecular Carcinogenesis Laboratory, Toxicology and Molecular Biology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health (NIOSH), Morgantown, WV, USA

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 7 SEP 2012

ISBN Information

Print ISBN: 9781119976097

Online ISBN: 9781118349045



  • transcriptomics, applications in epigenetic toxicology;
  • epigenetics study of mitotically heritable alterations in gene expression;
  • epigenetic, alterations in gene, DNA methylation/histone/RNA-mediated;
  • microarray analysis, global gene expression in biological samples;
  • microarray analysis of gene expression profiles;
  • microarray, for accurate/unbiased information in biological samples;
  • replication, enhancing confidence in microarray data;
  • microarray based on DNA property, hybridization facilitating binding


This chapter contains sections titled:

  • Introduction

  • Microarray analysis of gene expression profiles

  • Gene expression studies – challenges

  • Conclusions

  • Acknowledgments

  • Disclaimer

  • References