5. Molecular Epigenetic Changes Caused by Environmental Pollutants

  1. Saura C. Sahu
  1. Solange S. Lewis1,
  2. Gregory J. Weber2,
  3. Jennifer L. Freeman2 and
  4. Maria S. Sepúlveda1,2

Published Online: 8 AUG 2012

DOI: 10.1002/9781118349045.ch5

Toxicology and Epigenetics

Toxicology and Epigenetics

How to Cite

Lewis, S. S., Weber, G. J., Freeman, J. L. and Sepúlveda, M. S. (2012) Molecular Epigenetic Changes Caused by Environmental Pollutants, in Toxicology and Epigenetics (ed S. C. Sahu), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781118349045.ch5

Editor Information

  1. Division of Toxicology, Center for Food Safety and Applied Nutrition, Food and Drug Administration, Laurel, Maryland, USA

Author Information

  1. 1

    Department of Forestry and Natural Resources, Purdue University, West Lafayette, IN, USA

  2. 2

    School of Health Sciences, Purdue University, West Lafayette, IN, USA

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 7 SEP 2012

ISBN Information

Print ISBN: 9781119976097

Online ISBN: 9781118349045



  • environmental pollutants, and molecular epigenetic changes;
  • mechanisms of molecular epigenetic changes;
  • DNA methylation, in epigenetic, global or gene-specific;
  • epigenetic mechanisms of regulation, and DNA methylation;
  • histone modification assays, chromatin modification;
  • epigenetic changes induced by organic chemicals, EDCs;
  • molecular epigenetic effects, and organic contaminant exposure;
  • TCDD toxic dioxins in Agent Orange, herbicidal mixture;
  • metals, biological effects of chemical properties


This chapter contains sections titled:

  • Introduction

  • Mechanisms of molecular epigenetic changes

  • Epigenetic assays

  • Epigenetic changes induced by organic chemicals

  • Epigenetic changes induced by metals

  • Concluding remarks

  • References