5. Theoretical Framework IV: Gastrointestinal Transit Models and Integration

  1. Kiyohiko Sugano

Published Online: 8 AUG 2012

DOI: 10.1002/9781118354339.ch5

Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications

Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications

How to Cite

Sugano, K. (2012) Theoretical Framework IV: Gastrointestinal Transit Models and Integration, in Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118354339.ch5

Author Information

  1. Asahi Kasei Pharma Corp., Shizuoka, Japan

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 20 AUG 2012

ISBN Information

Print ISBN: 9781118028681

Online ISBN: 9781118354339

SEARCH

Keywords:

  • GI transit models;
  • small intestine, main absorption site;
  • three-compartment model;
  • convection–dispersion model;
  • analytical solution interpretation

Summary

This chapter contains sections titled:

  • GI Transit Models

  • Time-Dependent Changes of Physiological Parameters

  • Integration 1: Analytical Solutions

  • Integration 2: Numerical Integration

  • In Vivo FA From PK Data

  • Other Administration Routes

  • References