15. Historical Perspectives of Vasculitis

  1. Gary S. Hoffman MD, MS2,
  2. Cornelia M. Weyand MD, PhD3,
  3. Carol A. Langford MD, MHS2 and
  4. Jörg J. Goronzy MD, PhD3
  1. Eric Matteson MD, MPH

Published Online: 3 MAY 2012

DOI: 10.1002/9781118355244.ch15

Inflammatory Diseases of Blood Vessels, Second Edition

Inflammatory Diseases of Blood Vessels, Second Edition

How to Cite

Matteson, E. (2012) Historical Perspectives of Vasculitis, in Inflammatory Diseases of Blood Vessels, Second Edition (eds G. S. Hoffman, C. M. Weyand, C. A. Langford and J. J. Goronzy), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781118355244.ch15

Editor Information

  1. 2

    Department of Rheumatic and Immunologic Diseases, Center for Vasculitis Care and Research, Cleveland Clinic, Lerner College of Medicine, Cleveland, OH, USA

  2. 3

    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA

Author Information

  1. Divisions of Rheumatology and Epidemiology, Chair, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN, USA

Publication History

  1. Published Online: 3 MAY 2012
  2. Published Print: 8 JUN 2012

ISBN Information

Print ISBN: 9781444338225

Online ISBN: 9781118355244



  • History;
  • perspective;
  • classification;
  • vasculitis


Historical accounts of idiopathic vasculitis provide an important perspective for modern clinicians and researchers in understanding the evolution of current concepts of clinical vasculitis and its nosology and classification. Descriptions of large vessel vasculitis may date from the Middle Ages, with wider recognition and better understanding of inflammatory vessel disease coming in the nineteenth and early twentieth century with descriptions of polyarteritis nodosa, microscopic polyarteritis and granulomatous vasculitis, forming the foundation for current research and classification efforts.